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Join the RELIEF Study

Does urinary leaking control your life?

The RELIEF study is looking to improve treatment of urgency urinary leaking in older women by comparing two doses of bladder BOTOX© treatment.

We are now recruiting women ages 70 and older for this 15-month study at 6 study sites nationwide.

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The RELIEF (Reduced dose BOTOX© for urgency urinary incontinence among older women) Study is being conducted to improve treatment options for older women with urgency urinary incontinence (UUI). 

Urgency urinary incontinence (UUI) is when you feel a sudden, strong desire to pass urine that results in leakage before reaching the toilet. Many women find UUI very bothersome. BOTOX© is a safe and effective treatment option for women with UUI.

We are now recruiting women 70+ to participate in a 15-month study to compare 50 units and 100 units of bladder BOTOX©. As part of this study, you will be asked to: Complete several questionnaires about your medical history, including questions about your overactive bladder and incontinence history. You may also be invited to participate in a one-on-one interview where we would ask you questions about your experiences. 

Participants must:

  • Be 70 or older
  • Have moderate to severe urgency incontinence
  • Have health insurance that can cover BOTOX© treatment (we can help you figure this out!)
  • Come in person to one of our 6 research sites
  • Be willing to complete surveys and comply with study procedures

Participants must NOT:

  • Have had BOTOX© in the last year
  • Have severe difficulty emptying the bladder, or ‘neurogenic bladder’.

If you are interested in participating or want to learn more about the study, please reach out to the site nearest you:

Dartmouth-Hitchcock Medical Center, Lebanon, NH
Alessandra Bryan
University of Pittsburgh, Pittsburgh, PA
Lindsey Baranski
University of Alabama, Birmingham, AL
Sunita Patel
University of Texas – Southwestern, Dallas, TX
Jose Santoyo
Agnes Burris
Kaiser Permanente, San Diego, CA
Gisselle Zazueta-Damian
619-821-5717 or 619-221-6274
Linda M. Mackinnon
619-821-6009 or 619-221-6418
Oregon Health and Sciences University, Portland, OR
Yareli Cornejo-Torres


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