RELIEF Study

The RELIEF (Reduced dose BOTOX© for urgency urinary incontinence among older women) Study is being conducted to improve treatment options for older women with urgency urinary incontinence (UUI). 

Urgency urinary incontinence (UUI) is when you feel a sudden, strong desire to pass urine that results in leakage before reaching the toilet. Many women find UUI very bothersome. BOTOX© is a safe and effective treatment option for women with UUI.

We are now recruiting women 70+ to participate in a 15-month study to compare 50 units and 100 units of bladder BOTOX©. As part of this study, you will be asked to: Complete several questionnaires about your medical history, including questions about your overactive bladder and incontinence history. You may also be invited to participate in a one-on-one interview where we would ask you questions about your experiences. 

Participants must:

• Be 70 or older
• Have moderate to severe urgency incontinence
• Have health insurance that can cover BOTOX© treatment (we can help you figure this out!)
• Come in person to one of our 6 research sites
• Be willing to complete surveys and comply with study procedures

Participants must NOT:

• Have had BOTOX© in the last year
• Have severe difficulty emptying the bladder, or ‘neurogenic bladder’.

If you are interested in participating or want to learn more about the study, please reach out to the site nearest you:

Dartmouth-Hitchcock Medical Center, Lebanon, NH

• Alessandra Bryan
  [email protected]
  603-653-9993

University of Pittsburgh, Pittsburgh, PA

• Lindsey Baranski
  [email protected]
  412-641-7894

University of Alabama, Birmingham, AL

• Sunita Patel
  [email protected]
  205-996-0241

University of Texas – Southwestern, Dallas, TX

• Jose Santoyo
  [email protected]
  214-645-8764
• Agnes Burris
  [email protected]
  214-645-3833

Kaiser Permanente, San Diego, CA

• Gisselle Zazueta-Damian
  [email protected]
  619-821-5717 or 619-221-6274
• Linda M. Mackinnon
  [email protected]
  619-821-6009 or 619-221-6418

Oregon Health and Sciences University, Portland, OR

• Yareli Cornejo-Torres
  [email protected]
  503-494-3666

Or find us online at: www.reliefstudy.org